ncRNA name | hsa-miR-216a-5p |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | human UM cell lines, human embryonic kidney cell line HEK293T; UM samples |
Methods | luciferase reporter assay, qRT-PCR, CCK-8 assay, colony formation assay, positron emission tomography (PET), immunohistochemistry |
Expression pattern | down-regulated |
Functional description | Our findings provide clues regarding the role of miR-216a-5p as a tumor suppressor in uveal melanoma through the inhibition of HK2. |
PubMed ID | 29763606 |
Year | 2018 |
Title | MiR-216a-5p/Hexokinase 2 axis regulates uveal melanoma growth through modulation of Warburg effect. |
Drug-related ncRNA | NO |
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